This is a years-spanning story of the characters Shuichi Nitori and Yoshino Takatsuki. The former, a girl assigned male at birth, the latter, a boy assigned female at birth. One may think that in Japan, as in the West, the subject of transsexuality would be depicted in a sensationalist if not mocking fashion in popular media. Even in the rare cases where the subject is given the respect it deserves, it can quickly take a turn for the dark, dwelling in bigotry and hatred.
But read any review or description of this series and chances are you will come across the word 'gentle.' The work's gentle analysis; the work's gentle treatment; the work's gentle story telling. And, indeed, it is this gentleness that makes the series special.